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Functional Dissection of Streptococcus pyogenes M5 Protein: the Hypervariable Region is Essential for Virulence
The surface-localized M protein of Streptococcus pyogenes is a major virulence factor that inhibits phagocytosis, as determined ex vivo. Because little is known about the role of M protein in vivo we analyzed the contribution of different M protein regions to virulence, using the fibrinogen (Fg)-bin...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2749438/ https://ncbi.nlm.nih.gov/pubmed/19794915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007279 |
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