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To pool or not to pool, from whether to when: applications of pooling to biospecimens subject to a limit of detection

Pooling of biological specimens has been utilised as a cost-efficient sampling strategy, but cost is not the unique limiting factor in biomarker development and evaluation. We examine the effect of different sampling strategies of biospecimens for exposure assessment that cannot be detected below a...

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Detalhes bibliográficos
Main Authors: Schisterman, Enrique F., Vexler, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749284/
https://ncbi.nlm.nih.gov/pubmed/18782255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-3016.2008.00956.x
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