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To pool or not to pool, from whether to when: applications of pooling to biospecimens subject to a limit of detection

Pooling of biological specimens has been utilised as a cost-efficient sampling strategy, but cost is not the unique limiting factor in biomarker development and evaluation. We examine the effect of different sampling strategies of biospecimens for exposure assessment that cannot be detected below a...

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Autori principali: Schisterman, Enrique F., Vexler, Albert
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749284/
https://ncbi.nlm.nih.gov/pubmed/18782255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-3016.2008.00956.x
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