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Multivariate Normally Distributed Biomarkers Subject to Limits of Detection and Receiver Operating Characteristic Curve Inference

RATIONALE AND OBJECTIVES: Biomarkers are of ever-increasing importance to clinical practice and epidemiologic research. Multiple biomarkers are often measured per patient. Measurement of true biomarker levels is limited by laboratory precision, specifically measuring relatively low, or high, biomark...

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Detalhes bibliográficos
Main Authors: Perkins, Neil J., Schisterman, Enrique F., Vexler, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160911/
https://ncbi.nlm.nih.gov/pubmed/23747152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.acra.2013.04.001
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