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ROC curve inference for best linear combination of two biomarkers subject to limits of detection

The receiver operating characteristic (ROC) curve is a tool commonly used to evaluate biomarker utility in clinical diagnosis of disease. Often, multiple biomarkers are developed to evaluate the discrimination for the same outcome. Levels of multiple biomarkers can be combined via best linear combin...

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Detalhes bibliográficos
Main Authors: Perkins, Neil J., Schisterman, Enrique F., Vexler, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159257/
https://ncbi.nlm.nih.gov/pubmed/22223252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bimj.201000083
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