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ROC curve inference for best linear combination of two biomarkers subject to limits of detection

The receiver operating characteristic (ROC) curve is a tool commonly used to evaluate biomarker utility in clinical diagnosis of disease. Often, multiple biomarkers are developed to evaluate the discrimination for the same outcome. Levels of multiple biomarkers can be combined via best linear combin...

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Autores principales: Perkins, Neil J., Schisterman, Enrique F., Vexler, Albert
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159257/
https://ncbi.nlm.nih.gov/pubmed/22223252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bimj.201000083
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