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Interferon-inducible Immunity-Related GTPase Irgm1 regulates IFN-γ-dependent host defense, lymphocyte survival and autophagy
IFN-γ is a pleiotropic cytokine that plays a key role in host resistance yet when not properly regulated can become host-detrimental. The interferon-inducible Immunity Related GTPase family M member 1 (Irgm1), previously characterized as an effector molecule required for macrophage microbicidal acti...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2749220/ https://ncbi.nlm.nih.gov/pubmed/19066452 |
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