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Interferon-inducible Immunity-Related GTPase Irgm1 regulates IFN-γ-dependent host defense, lymphocyte survival and autophagy

IFN-γ is a pleiotropic cytokine that plays a key role in host resistance yet when not properly regulated can become host-detrimental. The interferon-inducible Immunity Related GTPase family M member 1 (Irgm1), previously characterized as an effector molecule required for macrophage microbicidal acti...

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Detalhes bibliográficos
Main Authors: Feng, Carl G., Zheng, Lixin, Lenardo, Michael J., Sher, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749220/
https://ncbi.nlm.nih.gov/pubmed/19066452
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