IFN-γ-Induced Macrophage Antileishmanial Mechanisms in Mice: A Role for Immunity- Related GTPases, Irgm1 and Irgm3, in Leishmania donovani Infection in the Liver

In C57BL/6 mice, Leishmania donovani infection in the liver provoked IFN-γ induced expression of the immunity-related GTPases (IRG), Irgm1 and Irgm3. To gauge the antileishmanial effects of these macrophage factors in the liver, intracellular infection was analyzed in IRG-deficient mice. In early- (...

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Detaylı Bibliyografya
Yayımlandı:Exp Parasitol
Asıl Yazarlar: Murray, Henry W., Mitchell-Flack, Marisa, Taylor, Gregory A., Ma, Xiaojing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640457/
https://ncbi.nlm.nih.gov/pubmed/26208780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exppara.2015.07.005
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