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IFN-γ-Induced Macrophage Antileishmanial Mechanisms in Mice: A Role for Immunity- Related GTPases, Irgm1 and Irgm3, in Leishmania donovani Infection in the Liver
In C57BL/6 mice, Leishmania donovani infection in the liver provoked IFN-γ induced expression of the immunity-related GTPases (IRG), Irgm1 and Irgm3. To gauge the antileishmanial effects of these macrophage factors in the liver, intracellular infection was analyzed in IRG-deficient mice. In early- (...
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| Publicado no: | Exp Parasitol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4640457/ https://ncbi.nlm.nih.gov/pubmed/26208780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exppara.2015.07.005 |
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