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The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation

Hematopoietic stem cells give rise to all blood lineages, and retain a remarkable capacity to proliferate in response to insult. While some controls on HSC activation are known, little is understood about how this process is linked to natural signals. We report that the interferon-inducible GTPase L...

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Autors principals: Feng, Carl G., Weksberg, David C., Taylor, Gregory A., Sher, Alan, Goodell, Margaret A.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278017/
https://ncbi.nlm.nih.gov/pubmed/18371424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2007.10.007
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