Vascular Endothelial Growth Factor (VEGF) Receptor-2 Tyrosine 1175 Signaling Controls VEGF-induced von Willebrand Factor Release from Endothelial Cells via Phospholipase C-γ1- and Protein Kinase A-dependent Pathways

There is increasing evidence that vascular endothelial growth factor (VEGF) contributes to inflammation independent of its angiogenic functions. Targeting some of the components in endothelial Weibel-Palade bodies (WPBs) effectively inhibits VEGF-induced inflammation, but little is known about how V...

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Bibliographische Detailangaben
Hauptverfasser: Xiong, Yan, Huo, Yingqing, Chen, Chao, Zeng, Huiyan, Lu, Xiaofan, Wei, Chaoliang, Ruan, Changgeng, Zhang, Xiaoyu, Hu, Zhenqian, Shibuya, Masabumi, Luo, Jincai
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Mechanisms of Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749095/
https://ncbi.nlm.nih.gov/pubmed/19570985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.019679
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