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Vascular Endothelial Growth Factor (VEGF) and Its Receptor (VEGFR) Signaling in Angiogenesis: A Crucial Target for Anti- and Pro-Angiogenic Therapies

The vascular endothelial growth factor (VEGF) and its receptor (VEGFR) have been shown to play major roles not only in physiological but also in most pathological angiogenesis, such as cancer. VEGF belongs to the PDGF supergene family characterized by 8 conserved cysteines and functions as a homodim...

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Detalles Bibliográficos
Autor Principal: Shibuya, Masabumi
Formato: Artigo
Idioma:Inglês
Publicado: SAGE Publications 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411125/
https://ncbi.nlm.nih.gov/pubmed/22866201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911423031
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