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Vascular Endothelial Growth Factor (VEGF) and Its Receptor (VEGFR) Signaling in Angiogenesis: A Crucial Target for Anti- and Pro-Angiogenic Therapies

The vascular endothelial growth factor (VEGF) and its receptor (VEGFR) have been shown to play major roles not only in physiological but also in most pathological angiogenesis, such as cancer. VEGF belongs to the PDGF supergene family characterized by 8 conserved cysteines and functions as a homodim...

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Bibliografiska uppgifter
Huvudupphovsman: Shibuya, Masabumi
Materialtyp: Artigo
Språk:Inglês
Publicerad: SAGE Publications 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411125/
https://ncbi.nlm.nih.gov/pubmed/22866201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911423031
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