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Vascular Endothelial Growth Factor (VEGF) and Its Receptor (VEGFR) Signaling in Angiogenesis: A Crucial Target for Anti- and Pro-Angiogenic Therapies

The vascular endothelial growth factor (VEGF) and its receptor (VEGFR) have been shown to play major roles not only in physiological but also in most pathological angiogenesis, such as cancer. VEGF belongs to the PDGF supergene family characterized by 8 conserved cysteines and functions as a homodim...

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書目詳細資料
主要作者: Shibuya, Masabumi
格式: Artigo
語言:Inglês
出版: SAGE Publications 2011
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411125/
https://ncbi.nlm.nih.gov/pubmed/22866201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911423031
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