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Vascular Endothelial Growth Factor (VEGF) and Its Receptor (VEGFR) Signaling in Angiogenesis: A Crucial Target for Anti- and Pro-Angiogenic Therapies
The vascular endothelial growth factor (VEGF) and its receptor (VEGFR) have been shown to play major roles not only in physiological but also in most pathological angiogenesis, such as cancer. VEGF belongs to the PDGF supergene family characterized by 8 conserved cysteines and functions as a homodim...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3411125/ https://ncbi.nlm.nih.gov/pubmed/22866201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911423031 |
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