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Vascular Endothelial Growth Factor (VEGF) and Its Receptor (VEGFR) Signaling in Angiogenesis: A Crucial Target for Anti- and Pro-Angiogenic Therapies

The vascular endothelial growth factor (VEGF) and its receptor (VEGFR) have been shown to play major roles not only in physiological but also in most pathological angiogenesis, such as cancer. VEGF belongs to the PDGF supergene family characterized by 8 conserved cysteines and functions as a homodim...

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Autore principale: Shibuya, Masabumi
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411125/
https://ncbi.nlm.nih.gov/pubmed/22866201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911423031
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