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Hypertensive stretch regulates endothelial exocytosis of Weibel-Palade bodies through VEGF receptor 2 signaling pathways

Regulated endothelial exocytosis of Weibel-Palade bodies (WPBs), the first stage in leukocyte trafficking, plays a pivotal role in inflammation and injury. Acute mechanical stretch has been closely associated with vascular inflammation, although the precise mechanism is unknown. Here, we show that h...

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Detalhes bibliográficos
Main Authors: Xiong, Yan, Hu, Zhenqian, Han, Xiaofan, Jiang, Beibei, Zhang, Rongli, Zhang, Xiaoyu, Lu, Yao, Geng, Chenyang, Li, Wei, He, Yulong, Huo, Yingqing, Shibuya, Masabumi, Luo, Jincai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674392/
https://ncbi.nlm.nih.gov/pubmed/23609797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.56
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