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Detection of Human CYP2C8, CYP2C9 and CYP2J2 in Cardiovascular Tissues

The cytochrome P450 (CYP) enzymes CYP2C8, CYP2C9, and CYP2J2 metabolize arachidonic acid to epoxyeicosatrienoic acids (EETs), which are known to be vital in regulation of vascular tone and cardiovascular homeostasis. Since there is limited information regarding the relative expression of these CYP e...

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Hlavní autoři: DeLozier, Tracy C., Kissling, Grace E., Coulter, Sherry J., Dai, Diana, Foley, Julie F., Bradbury, J. Alyce, Murphy, Elizabeth, Steenbergen, Charles, Zeldin, Darryl C., Goldstein, Joyce A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747652/
https://ncbi.nlm.nih.gov/pubmed/17220242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.106.012823
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