Expression of Cyp2c/Cyp2j subfamily members and oxylipin levels during LPS-induced inflammation and resolution in mice

Inflammatory stimuli, such as bacterial LPS, alter the expression of many cytochromes P450. CYP2C and CYP2J subfamily members actively metabolize fatty acids to bioactive eicosanoids, which exhibit potent anti-inflammatory effects. Herein, we examined mRNA levels of the 15 mouse Cyp2c and 7 mouse Cy...

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Dettagli Bibliografici
Pubblicato in:FASEB J
Autori principali: Graves, Joan P., Bradbury, J. Alyce, Gruzdev, Artiom, Li, Hong, Duval, Caroline, Lih, Fred B., Edin, Matthew L., Zeldin, Darryl C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894073/
https://ncbi.nlm.nih.gov/pubmed/31690125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901872R
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