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Characterization of the Tissue Distribution of the Mouse Cyp2c Subfamily by Quantitative PCR Analysis

The CYP2C subfamily of the cytochrome P450 gene superfamily encodes heme-thiolate proteins that have a myriad of biologic functions. CYP2C proteins detoxify xenobiotics and metabolize endogenous lipids such as arachidonic acid to bioactive eicosanoids. We report new methods and results for the quant...

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Библиографические подробности
Опубликовано в: :Drug Metab Dispos
Главные авторы: Graves, Joan P., Gruzdev, Artiom, Bradbury, J. Alyce, DeGraff, Laura M., Edin, Matthew L., Zeldin, Darryl C.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Pharmacology and Experimental Therapeutics 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478903/
https://ncbi.nlm.nih.gov/pubmed/28450579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.117.075697
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