Expression of Cyp2c/Cyp2j subfamily members and oxylipin levels during LPS-induced inflammation and resolution in mice

Inflammatory stimuli, such as bacterial LPS, alter the expression of many cytochromes P450. CYP2C and CYP2J subfamily members actively metabolize fatty acids to bioactive eicosanoids, which exhibit potent anti-inflammatory effects. Herein, we examined mRNA levels of the 15 mouse Cyp2c and 7 mouse Cy...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Graves, Joan P., Bradbury, J. Alyce, Gruzdev, Artiom, Li, Hong, Duval, Caroline, Lih, Fred B., Edin, Matthew L., Zeldin, Darryl C.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894073/
https://ncbi.nlm.nih.gov/pubmed/31690125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901872R
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