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Blocked inhibitory serine-phosphorylation of glycogen synthase kinase-3α/β impairs in vivo neural precursor cell proliferation

BACKGROUND: Adult neurogenesis augments neuronal plasticity, and deficient neurogenesis may contribute to mood disorders and schizophrenia and impede treatment responses. Since these diseases may be associated with inadequately controlled glycogen synthase kinase-3 (GSK3), we tested if blocked inhib...

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Detalhes bibliográficos
Main Authors: Eom, Tae-Yeon, Jope, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746934/
https://ncbi.nlm.nih.gov/pubmed/19520363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2009.04.015
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