Impairments in cognition and neural precursor cell proliferation in mice expressing constitutively active glycogen synthase kinase-3

Brain glycogen synthase kinase-3 (GSK3) is hyperactive in several neurological conditions that involve impairments in both cognition and neurogenesis. This raises the hypotheses that hyperactive GSK3 may directly contribute to impaired cognition, and that this may be related to deficiencies in neura...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Behav Neurosci
Prif Awduron: Pardo, Marta, King, Margaret K., Perez-Costas, Emma, Melendez-Ferro, Miguel, Martinez, Ana, Beurel, Eleonore, Jope, Richard S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2015
Pynciau:
Neuroscience
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349180/
https://ncbi.nlm.nih.gov/pubmed/25788881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2015.00055
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