Impairments in cognition and neural precursor cell proliferation in mice expressing constitutively active glycogen synthase kinase-3

Brain glycogen synthase kinase-3 (GSK3) is hyperactive in several neurological conditions that involve impairments in both cognition and neurogenesis. This raises the hypotheses that hyperactive GSK3 may directly contribute to impaired cognition, and that this may be related to deficiencies in neura...

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Dades bibliogràfiques
Publicat a:Front Behav Neurosci
Autors principals: Pardo, Marta, King, Margaret K., Perez-Costas, Emma, Melendez-Ferro, Miguel, Martinez, Ana, Beurel, Eleonore, Jope, Richard S.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2015
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349180/
https://ncbi.nlm.nih.gov/pubmed/25788881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2015.00055
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