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Lipopolysaccharide-induced interleukin-6 production is controlled by glycogen synthase kinase-3 and STAT3 in the brain

BACKGROUND: Septic shock is a prevalent condition that, when not lethal, often causes disturbances in cognition, mood, and behavior, particularly due to central actions of the inflammatory cytokine interleukin-6 (IL-6). To identify potential targets to control brain IL-6, we tested if IL-6 produced...

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Detalhes bibliográficos
Principais autores: Beurel, Eléonore, Jope, Richard S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660311/
https://ncbi.nlm.nih.gov/pubmed/19284588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-6-9
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