Deficiency in the Inhibitory Serine-Phosphorylation of Glycogen Synthase Kinase-3 Increases Sensitivity to Mood Disturbances

Bipolar disorder, characterized by extreme manic and depressive moods, is a prevalent debilitating disease of unknown etiology. Because mood stabilizers, antipsychotics, antidepressants, and mood-regulating neuromodulators increase the inhibitory serine-phosphorylation of glycogen synthase kinase-3...

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Main Authors: Polter, Abigail, Beurel, Eléonore, Yang, Sufen, Garner, Rakesha, Song, Ling, Miller, Courtney A, Sweatt, J David, McMahon, Lori, Bartolucci, Alfred A, Li, Xiaohua, Jope, Richard S
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2010
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891528/
https://ncbi.nlm.nih.gov/pubmed/20357757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.43
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