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Blocked inhibitory serine-phosphorylation of glycogen synthase kinase-3α/β impairs in vivo neural precursor cell proliferation

BACKGROUND: Adult neurogenesis augments neuronal plasticity, and deficient neurogenesis may contribute to mood disorders and schizophrenia and impede treatment responses. Since these diseases may be associated with inadequately controlled glycogen synthase kinase-3 (GSK3), we tested if blocked inhib...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Eom, Tae-Yeon, Jope, Richard S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746934/
https://ncbi.nlm.nih.gov/pubmed/19520363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2009.04.015
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