ICOS Controls Effector Function but Not Trafficking Receptor Expression of Kidney-Infiltrating Effector T Cells in Murine Lupus

Renal pathology in systemic lupus erythematosus involves both autoantibody deposition and a cellular inflammatory response, both of which are mediated by effector CD4 T cells. MRL(lpr) mice spontaneously develop massive perivascular infiltrates, but the pathways that regulate the development, traffi...

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Главные авторы: Odegard, Jared M., DiPlacido, Leah D., Greenwald, Lark, Kashgarian, Michael, Kono, Dwight H., Dong, Chen, Flavell, Richard A., Craft, Joe
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746004/
https://ncbi.nlm.nih.gov/pubmed/19299705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0800758
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