ABCG2 Is Upregulated in Alzheimer's Brain with Cerebral Amyloid Angiopathy and May Act as a Gatekeeper at the Blood–Brain Barrier for Aβ(1–40) Peptides

Alzheimer's disease (AD) is characterized by accumulation and deposition of Aβ peptides in the brain. Aβ deposition in cerebrovessels occurs in many AD patients and results in cerebral amyloid angiopathy (AD/CAA). Since Aβ can be transported across blood–brain barrier (BBB), aberrant Aβ traffic...

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Autores principales: Xiong, Huaqi, Callaghan, Debbie, Jones, Aimee, Bai, Jianying, Rasquinha, Ingrid, Smith, Catherine, Pei, Ke, Walker, Douglas, Lue, Lih-Fen, Stanimirovic, Danica, Zhang, Wandong
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2009
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745912/
https://ncbi.nlm.nih.gov/pubmed/19403814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5103-08.2009
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