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A PTB-dependent Program of mRNA Stability Initiates with CpG-mediated Activation of Primary B cells

The mRNA encoding CD154, a critical protein involved in both humoral and cell-mediated immune responses, is regulated at the post-transcriptional level by the binding of Complex I, a polypyrimidine tract-binding protein (PTB) containing complex, which acts to increase message stability at late times...

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Autors principals: Porter, Joseph F., Vavassori, Stefano, Covey, Lori R.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745733/
https://ncbi.nlm.nih.gov/pubmed/18714005
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