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PTB is Critical for the Turnover and Subcellular Distribution of CD40 Ligand (CD40L) mRNA in CD4(+) T cells

CD40 ligand (CD40L or CD154) is regulated at the posttranscriptional level by an activation-induced process that results in a highly stable transcript at extended times of T cell activation. Transcript stability is mediated by polypyrimidine tract-binding protein (PTB)-containing complexes (Complex...

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Detalhes bibliográficos
Main Authors: Matus-Nicodemos, Rodrigo, Vavassori, Stefano, Castro-Faix, Moraima, Valentin-Acevedo, Anibal, Singh, Karnail, Marcelli, Valentina, Covey, Lori R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119477/
https://ncbi.nlm.nih.gov/pubmed/21242519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003236
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