Low expression of γ-glutamyl hydrolase mRNA in primary colorectal cancer with the CpG island methylator phenotype

The CpG island methylator phenotype (CIMP+) in colorectal cancer (CRC) is defined as concomitant and frequent hypermethylation of CpG islands within gene promoter regions. We previously demonstrated that CIMP+ was associated with elevated concentrations of folate intermediates in tumour tissues. In...

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Detalhes bibliográficos
Main Authors: Kawakami, K, Ooyama, A, Ruszkiewicz, A, Jin, M, Watanabe, G, Moore, J, Oka, T, Iacopetta, B, Minamoto, T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2391094/
https://ncbi.nlm.nih.gov/pubmed/18414409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604346
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