RNase L Mediated Protection from Virus Induced Demyelination

IFN-α/β plays a critical role in limiting viral spread, restricting viral tropism and protecting mice from neurotropic coronavirus infection. However, the IFN-α/β dependent mechanisms underlying innate anti-viral functions within the CNS are poorly understood. The role of RNase L in viral encephalom...

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Autori principali: Ireland, Derek D. C., Stohlman, Stephen A., Hinton, David R., Kapil, Parul, Silverman, Robert H., Atkinson, Roscoe A., Bergmann, Cornelia C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745574/
https://ncbi.nlm.nih.gov/pubmed/19798426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000602
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