Immunogenicity of the Hu14.18-IL2 Immunocytokine Molecule in Adults with Melanoma and Children with Neuroblastoma

PURPOSE: Immunocytokine (IC) hu14.18-IL2 is a fusion protein of humanized anti-disialoganglioside (GD2) antibody (hu14.18) and interleukin-2. Sixty-one melanoma and neuroblastoma patients received IC in Phase I/Ib studies. Patient sera were examined in enzyme-linked immunosorbent assay (ELISA) to de...

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Detaylı Bibliyografya
Asıl Yazarlar: Hank, Jacquelyn A., Gan, Jacek, Ryu, Hyunji, Ostendorf, Amy, Stauder, Michael C., Sternberg, Adam, Albertini, Mark, Lo, Kin-Ming, Gillies, Stephen D., Eickhoff, Jens, Sondel, Paul M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745522/
https://ncbi.nlm.nih.gov/pubmed/19737959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-2963
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