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Immunogenicity of the Hu14.18-IL2 Immunocytokine Molecule in Adults with Melanoma and Children with Neuroblastoma
PURPOSE: Immunocytokine (IC) hu14.18-IL2 is a fusion protein of humanized anti-disialoganglioside (GD2) antibody (hu14.18) and interleukin-2. Sixty-one melanoma and neuroblastoma patients received IC in Phase I/Ib studies. Patient sera were examined in enzyme-linked immunosorbent assay (ELISA) to de...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2745522/ https://ncbi.nlm.nih.gov/pubmed/19737959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-2963 |
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