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Development and cancer: At the crossroads of Nodal and Notch signaling

Aggressive tumor cells express a plastic, multipotent phenotype similar to embryonic stem cells. However, the absence of major regulatory checkpoints in these tumor cells allows aberrant activation of embryonic signaling pathways, which appears to contribute to their plastic phenotype. Emerging evid...

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Autors principals: Strizzi, Luigi, Hardy, Katharine M., Seftor, Elisabeth A., Costa, Fabricio F., Kirschmann, Dawn A., Seftor, Richard E.B., Postovit, Lynne-Marie, Hendrix, Mary J.C.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745492/
https://ncbi.nlm.nih.gov/pubmed/19738053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1199
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