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Increase in Thiol Oxidative Stress via Glutathione Reductase Inhibition as a Novel Approach to Enhance Cancer Sensitivity to X-Ray Irradiation

Depletion of reduced form glutathione (GSH) has been extensively studied for its effect on sensitizing cancer to radiation. However, little is known about the effect of thiol oxidative stress created through an increase in glutathione disulfide (GSSG) on cancer sensitivity to radiation. In this stud...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Zhao, Yong, Seefeldt, Teresa, Chen, Wei, Carlson, Laura, Stoebner, Adam, Hanson, Sarah, Foll, Ryan, Matthees, Duane P., Palakurthi, Srinath, Guan, Xiangming
التنسيق: Artigo
اللغة:Inglês
منشور في: 2009
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745482/
https://ncbi.nlm.nih.gov/pubmed/19397999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2009.04.022
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