Increase in Thiol Oxidative Stress via Glutathione Reductase Inhibition as a Novel Approach to Enhance Cancer Sensitivity to X-Ray Irradiation

Depletion of reduced form glutathione (GSH) has been extensively studied for its effect on sensitizing cancer to radiation. However, little is known about the effect of thiol oxidative stress created through an increase in glutathione disulfide (GSSG) on cancer sensitivity to radiation. In this stud...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhao, Yong, Seefeldt, Teresa, Chen, Wei, Carlson, Laura, Stoebner, Adam, Hanson, Sarah, Foll, Ryan, Matthees, Duane P., Palakurthi, Srinath, Guan, Xiangming
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745482/
https://ncbi.nlm.nih.gov/pubmed/19397999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2009.04.022
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