Transchromosomic cell model of Down syndrome shows aberrant migration, adhesion and proteome response to extracellular matrix

BACKGROUND: Down syndrome (DS), caused by trisomy of human chromosome 21 (HSA21), is the most common genetic birth defect. Congenital heart defects (CHD) are seen in 40% of DS children, and >50% of all atrioventricular canal defects in infancy are caused by trisomy 21, but the causative genes rem...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Delom, Frédéric, Burt, Emma, Hoischen, Alex, Veltman, Joris, Groet, Jürgen, Cotter, Finbarr E, Nizetic, Dean
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2009
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745369/
https://ncbi.nlm.nih.gov/pubmed/19715584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5956-7-31
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares