Transchromosomic cell model of Down syndrome shows aberrant migration, adhesion and proteome response to extracellular matrix

BACKGROUND: Down syndrome (DS), caused by trisomy of human chromosome 21 (HSA21), is the most common genetic birth defect. Congenital heart defects (CHD) are seen in 40% of DS children, and >50% of all atrioventricular canal defects in infancy are caused by trisomy 21, but the causative genes rem...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Delom, Frédéric, Burt, Emma, Hoischen, Alex, Veltman, Joris, Groet, Jürgen, Cotter, Finbarr E, Nizetic, Dean
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2009
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745369/
https://ncbi.nlm.nih.gov/pubmed/19715584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5956-7-31
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk