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A structure-based view of Epidermal Growth Factor Receptor regulation
High-resolution X-ray crystal structures determined in the past six years dramatically influence our view of ligand induced activation of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. Ligand binding to the extracellular region of EGFR promotes a major domain reorga...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2745238/ https://ncbi.nlm.nih.gov/pubmed/18573086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.biophys.37.032807.125829 |
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