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Epidermal growth factor receptor structural alterations in gastric cancer

BACKGROUND: EGFR overexpression has been described in many human tumours including gastric cancer. In NSCLC patients somatic EGFR mutations, within the kinase domain of the protein, as well as gene amplification were associated with a good clinical response to EGFR inhibitors. In gastric tumours dat...

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Detalhes bibliográficos
Main Authors: Moutinho, Cátia, Mateus, Ana R, Milanezi, Fernanda, Carneiro, Fátima, Seruca, Raquel, Suriano, Gianpaolo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2244615/
https://ncbi.nlm.nih.gov/pubmed/18199332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-10
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