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Epidermal growth factor receptor structural alterations in gastric cancer

BACKGROUND: EGFR overexpression has been described in many human tumours including gastric cancer. In NSCLC patients somatic EGFR mutations, within the kinase domain of the protein, as well as gene amplification were associated with a good clinical response to EGFR inhibitors. In gastric tumours dat...

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Autori principali: Moutinho, Cátia, Mateus, Ana R, Milanezi, Fernanda, Carneiro, Fátima, Seruca, Raquel, Suriano, Gianpaolo
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2244615/
https://ncbi.nlm.nih.gov/pubmed/18199332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-10
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