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Salvinorin A and derivatives: protection from metabolism does not prolong short-term, whole-brain residence
Salvinorin A (SA) is a potent kappa opioid with a brief duration of action. Consistent with this, our previous positron emission tomography (PET) studies of carbon-11 labeled SA showed that brain levels decrease rapidly after intravenous administration. SA is rapidly metabolized, giving the much les...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2745083/ https://ncbi.nlm.nih.gov/pubmed/19591852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2009.06.044 |
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