Standard Protecting Groups Create Potent and Selective κ Opioids: Salvinorin B Alkoxymethyl Ethers

Protection of salvinorin B as standard alkoxyalkyl ethers yielded highly potent κ opioid receptor agonists. Ethoxymethyl ether 6 is among the most potent and selective κ agonists reported to date. Fluoroethoxymethyl ether 11 is the first potent, selective fluorinated κ ligand, with potential use in...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Munro, Thomas A., Duncan, Katharine K., Xu, Wei, Wang, Yulin, Liu-Chen, Lee-Yuan, Carlezon, William A., Cohen, Bruce M., Béguin., Cécile
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2568987/
https://ncbi.nlm.nih.gov/pubmed/17981041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.10.067
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