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IL-12 P40 Homodimer, the So-Called Biologically Inactive Molecule, Induces Nitric Oxide Synthase in Microglia via IL-12Rβ1

Earlier we have demonstrated that IL-12 p40 homodimer (p40(2)) induces the expression of inducible nitric oxide synthase (iNOS) in microglia. This study was undertaken to investigate underlying mechanisms required for IL-12 p40(2)- and IL-12 p70-induced expression of iNOS in microglia. IL-12 p40(2)...

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Detalhes bibliográficos
Main Authors: JANA, MALABENDU, DASGUPTA, SUBHAJIT, PAL, UTPAL, PAHAN, KALIPADA
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744843/
https://ncbi.nlm.nih.gov/pubmed/19306359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.20869
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