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Myelin Basic Protein-primed T Cells of Female but Not Male Mice Induce Nitric-oxide Synthase and Proinflammatory Cytokines in Microglia: IMPLICATIONS FOR GENDER BIAS IN MULTIPLE SCLEROSIS

Females are more susceptible than males to multiple sclerosis (MS). However, the underlying mechanism behind this gender difference is poorly understood. Because the presence of neuroantigen-primed T cells within the CNS is necessary for the development of MS, the present study was undertaken to inv...

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Detalhes bibliográficos
Main Authors: Dasgupta, Subhajit, Jana, Malabendu, Liu, Xiaojuan, Pahan, Kalipada
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1955478/
https://ncbi.nlm.nih.gov/pubmed/16046404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M500299200
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