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Induction of lymphotoxin-α by interleukin-12 p40 homodimer, the so-called biologically inactive molecule, but not IL-12 p70

Interleukin-12 (IL-12) p70 (p40:p35) is a bioactive cytokine and its biological functions are becoming clear. On the other hand, the IL-12 p40 homodimer (p40(2)) was considered an inactive or inhibitory molecule and its functions are poorly understood. It has been reported that increased expression...

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Bibliografiske detaljer
Main Authors: Jana, Malabendu, Pahan, Kalipada
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712100/
https://ncbi.nlm.nih.gov/pubmed/19019087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.02985.x
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