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Induction of tumor necrosis factor-α (TNF-α) by interleukin-12 p40 monomer and homodimer in microglia and macrophages
The present study was undertaken to explore the role of interleukin-12 (IL-12) p40 in the expression of TNF-α in microglia. Interestingly, we have found that IL-12 p70, p40(2) (the p40 homodimer) and p40 (the p40 monomer) dose-dependently induced the production of TNF-α and the expression of TNF-α m...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2003
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1955470/ https://ncbi.nlm.nih.gov/pubmed/12871593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1471-4159.2003.01864.x |
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