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Protective Effect of Delayed Treatment With Low-Dose Glibenclamide in Three Models of Ischemic Stroke
BACKGROUND AND PURPOSE: Ischemia/hypoxia induces de novo expression of the sulfonylurea receptor 1-regulated NC(Ca-ATP) channel. In rodent models of ischemic stroke, early postevent administration of the sulfonylurea, glibenclamide, is highly effective in reducing edema, mortality, and lesion volume...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2744391/ https://ncbi.nlm.nih.gov/pubmed/19023097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.108.522409 |
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