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Comparative effects of glibenclamide and riluzole in a rat model of severe cervical spinal cord injury

Both glibenclamide and riluzole reduce necrosis and improve outcome in rat models of spinal cord injury (SCI). In SCI, gene suppression experiments show that newly upregulated sulfonylurea receptor 1 (Sur1)-regulated NC(Ca-) ATP channels in microvascular endothelial cells are responsible for “persis...

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Detalhes bibliográficos
Main Authors: Simard, J. Marc, Tsymbalyuk, Orest, Keledjian, Kaspar, Ivanov, Alexander, Ivanova, Svetlana, Gerzanich, Volodymyr
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272255/
https://ncbi.nlm.nih.gov/pubmed/22177998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2011.11.044
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