Comparative effects of glibenclamide and riluzole in a rat model of severe cervical spinal cord injury

Both glibenclamide and riluzole reduce necrosis and improve outcome in rat models of spinal cord injury (SCI). In SCI, gene suppression experiments show that newly upregulated sulfonylurea receptor 1 (Sur1)-regulated NC(Ca-) ATP channels in microvascular endothelial cells are responsible for “persis...

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Bibliographic Details
Main Authors: Simard, J. Marc, Tsymbalyuk, Orest, Keledjian, Kaspar, Ivanov, Alexander, Ivanova, Svetlana, Gerzanich, Volodymyr
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272255/
https://ncbi.nlm.nih.gov/pubmed/22177998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2011.11.044
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