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Comparative effects of glibenclamide and riluzole in a rat model of severe cervical spinal cord injury
Both glibenclamide and riluzole reduce necrosis and improve outcome in rat models of spinal cord injury (SCI). In SCI, gene suppression experiments show that newly upregulated sulfonylurea receptor 1 (Sur1)-regulated NC(Ca-) ATP channels in microvascular endothelial cells are responsible for “persis...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3272255/ https://ncbi.nlm.nih.gov/pubmed/22177998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2011.11.044 |
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