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Glibenclamide is superior to decompressive craniectomy in a model of malignant stroke

BACKGROUND AND PURPOSE: Treating patients with malignant cerebral infarctions remains a major unsolved problem in medicine. Decompressive craniectomy (DC) improves the bleak outlook, but is suboptimal. Here, using a rat model of severe ischemia / reperfusion (I/R) with very high mortality due to mal...

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Библиографические подробности
Главные авторы: Simard, J. Marc, Tsymbalyuk, Natalia, Tsymbalyuk, Orest, Ivanova, Svetlana, Yurovsky, Vladimir, Gerzanich, Volodymyr
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845311/
https://ncbi.nlm.nih.gov/pubmed/20093633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.109.572644
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