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Adenylyl cyclase-5 activity in the nucleus accumbens regulates anxiety-related behaior

Type 5 adenylyl cyclase (AC5) is highly concentrated in the dorsal striatum and nucleus accumbens (NAc), two brain areas which have been implicated in motor function, reward, and emotion. Here we demonstrate that mice lacking AC5 (AC5−/−) display strong reductions in anxiety-like behavior in several...

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Hlavní autoři: Kim, Kyoung-Shim, Lee, Ko-Woon, Baek, In-Sun, Lim, Chae-Moon, Krishnan, Vaishnav, Lee, Ja-Kyeong, Nestler, Eric J., Han, Pyung-Lim
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744302/
https://ncbi.nlm.nih.gov/pubmed/18673448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05592.x
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