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Adenylyl cyclase type 5 (AC5) is an essential mediator of morphine action

Opioid drugs produce their pharmacological effects by activating inhibitory guanine nucleotide-binding regulatory protein-linked μ, δ, and κ opioid receptors. One major effector for these receptors is adenylyl cyclase, which is inhibited upon receptor activation. However, little is known about which...

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Main Authors: Kim, Kyoung-Shim, Lee, Ko-Woon, Lee, Kang-Woo, Im, Joo-Young, Yoo, Ji Yeoun, Kim, Seung-Woo, Lee, Ja-Kyeong, Nestler, Eric J., Han, Pyung-Lim
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1533788/
https://ncbi.nlm.nih.gov/pubmed/16537460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508812103
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