The Polycomb Group Gene Bmi1 Regulates Antioxidant Defenses in Neurons by Repressing p53 Pro-Oxidant Activity

Aging may be determined by a genetic program and/or by the accumulation rate of molecular damages. Reactive oxygen species (ROS) generated by the mitochondrial metabolism have been postulated to be the central source of molecular damages and imbalance between levels of intracellular ROS and antioxid...

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Main Authors: Chatoo, Wassim, Abdouh, Mohamed, David, Jocelyn, Champagne, Marie-Pier, Ferreira, José, Rodier, Francis, Bernier, Gilbert
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744209/
https://ncbi.nlm.nih.gov/pubmed/19144853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5303-08.2009
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